![]() ![]() The women who chose medical abortion were asked to take 25 mg mifepristone orally every 12 h for 3 days. Women with asthma or spasmodic bronchitis, impairment of liver or kidney function, long-term corticosteroid treatment, hemorrhagic disorder or treatment with anticoagulants, known allergy to mifepristone, breast-feeding, multiple gestation, genital tract infection, in situ intrauterine devices, adnexal masses, and severe cardiac disease were excluded. Women aged over 18 years, with a confirmed viable singleton intrauterine pregnancy of up to 49 days of gestation as assessed by pelvic ultrasound were included. Eligible women were given the choice of either a surgical or medical method and were subsequently classified into one of two groups. Women with gestation of up to 49 days seeking abortion at the out-patient department of the Department of Obstetrics and Gynecology, First Municipal Hospital of Guangzhou from January 1, 2008, to March 31, 2008, were included in this study. We compared the clinical efficacy, complications, side effects and direct costs of the two abortion methods for gestation up to 49 days in Guangzhou, the most developed city in South China. With the limitation of health care resources and the increasing pressure on reducing health care expenses in developing countries, determining cost-effective means for women seeking termination of pregnancy is an important clinical as well as public health concern. Clinical effectiveness, complications, side effects and acceptability of medical versus surgical abortions has been investigated in many studies, but little attention has been paid to the economic impacts of these two approaches, especially in developing countries. Complications of persistent bleeding and failure to abort (requiring surgical intervention) in the medical treatment group increased the final mean total cost substantially.Ī combination of mifepristone followed by a prostaglandin analogue is currently the most widely used regimen for medical abortion. ![]() Conclusions: There was no difference in the mean final costs between the two abortion methods. Patients undergoing medical abortion eventually incurred equivalent expenses compared to patients undergoing surgical abortion (p = 0.42). ![]() When the subsequent costs were accumulated within the 2-week follow-up, the mean total cost in the medical group increased significantly due to failure of abortion and persistent bleeding. Surgical abortion incurred much more costs than medical abortion on average after initial treatment. The efficacy in the surgical group was significantly higher than in the medical group (100 vs. Results: 219 subjects (51%) chose a medical method (mifepristone and misoprostol), whereas 211 subjects (49%) chose a surgical method. Cost-minimization analysis was used based on all charges for the overall procedures in an out-patient clinic in Guangzhou, China. We adopted the perspective of a third-party payer. Either a medical or surgical method was used for the abortion. ![]() Methods: 430 women seeking abortions were recruited in 2008. However, the monetary costs of these two methods have not been compared. Background: Both medical and surgical abortions are popular in developing countries. ![]()
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